Precision Diagnostics

From a single serum sample, we quantify multiple biomarkers — known and newly discovered. Advanced. Automated. Affordable.

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AXINON® System

FDA-cleared AXINON®System is our core technology platform. It incorporates diagnostic testing algorithms into nuclear magnetic resonance (NMR) spectroscopy.

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Axinon system with implemented and expandable test overview

AXINON® System. |Precision Diagnostics.

The proprietary AXINON® System  - now with FDA clearance - incorporates diagnostic testing algorithms into nuclear magnetic resonance (NMR) spectroscopy. We use this technology to develop diagnostic tests for chronic heart, kidney and liver diseases. 

The AXINON® System is the first modular software-based system for clinical diagnostics, providing hardware, operating system, Magnetic Group Signaling (MGS®) processor and individual test applications. It provides the framework for analyzing serum samples using nuclear magnetic resonance (NMR) spectroscopy.

  •           Innovative, real-time availability of metabolomic data
  •           Precise results for specific medical questions and diagnostic decisions
  •           Standardized analysis
  •           Multi-testing capability with high throughput
  •                   Fully automated lab solution
  •                   High reproducibility (inter-laboratory precision)
  •                   LIS/LIMS integration
  •                   Easy to use
Axinon system with implemented and expandable test overview

Platform

The NMR-based AXINON® System offers high throughput multi-testing capability

Precision

AXINON® enables a more detailed, standardized and automated metabolomic profile

Performance

We identify over 400 metabolites in one NMR run, enabling fast discovery of meaningful metabolomic profiles

Numares licenses the FDA-cleared AXINON® System, software, Magnetic Group Signaling (MGS®) technology, research methods and applications underlying our diagnostic products* to clients in the health care industry. For an individual licensing agreement, contact us.

Magnetic Group Signaling. |Next-Generation NMR Use.

Magnetic Group Signaling (MGS®) powers the AXINON® System. MGS® enables AXINON® to reproducibly elucidate metabolite data using NMR (nuclear magnetic resonance) spectroscopy, providing the information for precision diagnostic testing.

  • AI-based standardized algorithms
  • Reproducible multi-variable signal fitting
  • Quantitative multi-signal interpretation
  • Validated extraction of information from NMR spectra
  • Sophisticated SCORE calculation

“With MGS®, we evolved NMR to a fully automated system applicable to routine analysis. It enables diagnostics with excellent precision and comparability. MGS®-generated data can be analysed by several other AXINON® tests to reveal new diagnostic information.”

Dr. Daniela Baumstark

Head of Lipoprotein Analysis and Data Processing

Identifying Metabolites with AI-Enabled Technology

Finding metabolite constellations among hundreds of signals isn't easy.

We use machine learning to analyze data together with NMR metabolite measurements to identify the biomarkers carrying the most information for a certain disease. We then build an equation representing the metabolite constellation, with the equation used as a diagnostic test.

With machine learning, we use sophisticated algorithms to identify the signals from a single serum sample, like a blood or urine test. This information provides specific information about an individual.

*For Research Use only in the United States. Most Numares products are not yet available for sale in the United States; they have not yet been approved or cleared by the U.S. Food and Drug Administration. However, the AXINON® LDL-p Test System and the AXINON®System are cleared by the FDA and available for sale.

Video Tutorials

Numares video tutorials provide support for AXINON® System installation, operation and maintenance of AXINON® Software, NMR spectroscopy hardware and diagnostic software test applications.

For questions, contact our Technical Support.

Daily NMR Maintenance and Qualification - Video Tutorials

 
Learn how to monitor the liquid nitrogen levels of the AXINON System*. This version doesn't have audio.
 
Learn how to check the gradient image of the AXINON System*. This version doesn't have audio.
 
Learn how to check for noise in the AXINON System*. This version doesn't have audio.
 
Learn how to check the temperature of SampleJet cooling positions of the AXINON System*. This version doesn't have audio.
 
Learn how to check the status of the NMR console of the AXINON System*. This version doesn't have audio.

Further NMR Maintenance Video Tutorials

 
Learn how easy it is to use high-throughput NMR diagnostics with the AXINON System*. This version doesn't have audio.
 
Learn how easy it is to use NMR diagnostics with the AXINON System*. This version doesn't have audio.
 
Learn how to reboot the AXINON System*. This version doesn't have audio.
 
Learn how to exchange the NMR pincer*. This version doesn't have audio.
 
Learn how to clean the NMR probe*. This version doesn't have audio.

* For Research Use only in the United States. numares’ products are not yet available for sale in the United States and are not yet approved or cleared by the U.S. Food and Drug Administration.

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