High-throughput diagnostics with NMR
numares HEALTH develops innovative diagnostic tests based on nuclear magnetic resonance (NMR) spectroscopy for various indications. With the AXINONplatform, numares HEALTH offers a reliable, fast and flexible analysis system intended for use in medical laboratories. Used in conjunction with AXINON, the test lipoFIT-S100 for example allows the size distribution of lipoproteins in serum to be determined in high throughput.
Metabolomics in clinical use and laboratory diagnostics
Additional diagnostic tests are undergoing development at numares HEALTH. The basis of the test developments is the human metabolome that mirrors pathophysiological changes. The NMR spectroscopic detection of all metabolic products (metabolites), e. g. in serum or urine, opens up a unique insight into the processes and changes in the metabolism of (incipient) diseases.
Examples of diagnostic test development with NMR
Based on well-characterized patient populations, numares HEALTH evaluates the importance of lipoprotein subfractions for the risk assessment of cardiovascular diseases and for the early detection of diabetes mellitus and congenital lipid metabolic disorders (dyslipidemia). In the field of transplantation, numares HEALTH investigates the mechanisms associated with kidney graft rejection. The aim of research in this area is to develop a non-invasive diagnostic test that can reliably identify a graft rejection early on. In oncology, the aim is to use metabolite signatures for the diagnosis, follow-up and support of therapeutic decisions. numares HEALTH is currently developing a urine-based test for the diagnosis and classification of prostate cancer. All tests will be usable via NMR as a high-throughput application in clinical routine.
At the Forum Life Science in Garching (Booth #10), a multidisciplinary team of experienced scientists will answer all questions from interested visitors regarding the possibilities of NMR technology.
Dipl.-Biol. Christiane Proll, MBA
Tel.: +49 941 2809 49-14
IRA WÜLFING KOMMUNIKATION GmbH
Dr. Reinhard Saller
Tel.: +49 89 2000 30-38